The Tzanck smear assay is a cytological, morphological examination method that was used for many years for the diagnosis of various skin and mucocutaneous infections with HSV and VZV. The Tzanck smear must be performed by someone experienced in using the technique and interpreted by someone who can confidently and correctly distinguish herpesvivus nuclear inclusions from ... Another diagnostic method that can be done in the office is the Tzanck smear technique.

Context Explanation

This method involves scraping the lesions and visualizing the cells under a microscope (see Figure 7).