segmental hyperpigmentation - HEALTHY
Segmental macular hyperpigmentation (SMH) is macular hyperpigmentation in a defined developmental pattern, presenting at birth or in the early years. The only known cause of this phenotype has been mosaicism of gene GNAS, as part of McCune–Albright syndrome. Hyperpigmentation is common in dark skin and occurs when an area of skin becomes darker than the surrounding skin.
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It is typically longer lasting and more challenging to treat in darker than lighter ... Hyperpigmentation is darker patches from excess melanin, often more severe and longer lasting in dark skin. It can affect quality of life due as a result of the stress it can cause. A dermatologist ...
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Dark spots, stubborn patches, uneven tone — hyperpigmentation shows up in many ways and for just as many reasons. If you’ve ever wondered why some areas of your skin seem to darken out of nowhere (or ... When you think about hyperpigmentation, you probably think of your face. But this form of discoloration doesn’t just occur above the neck. It can show up anywhere on the body — even your buttocks.
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If ... Segmental pigmentation disorder (SegPD) refers to a subset of localised cutaneous pigmentary anomalies without systemic manifestations. It is characterised by unilateral hypo- or hyperpigmented patches, predominantly on the frontal torso with a sharp midline delineation. Segmental lentiginosis should be differentiated from other segmental disorders including speckled lentiginous nevus, segmental NF and agminated Spitz nevi. Wood's light examination and skin biopsy may be helpful in these cases. This topic will review the approach to the patient with congenital and inherited hyperpigmentation disorders.
Incontinentia pigmenti, pigmentary mosaicism, and acquired disorders of pigmentation, including melasma, are discussed separately.