Panniculitis with systemic features Associated symptoms of fever, malaise and arthralgia are common in patients with panniculitis. When these are prominent, diagnoses to consider include: Cutaneous vasculitis Infective panniculitis Subcutaneous acute febrile neutrophilic dermatosis Panniculitis associated with pancreatic disease Alpha-1-antitrypsin deficiency panniculitis Cytophagic ... What is panniculitis?

Context Explanation

Panniculitis is inflammation of subcutaneous fat. Despite having diverse causes, most forms of panniculitis have the same clinical appearance. What is panniculitis associated with pancreatic disease? Pancreatic panniculitis is the inflammation of subcutaneous fat associated with pancreatic disease, most commonly: Pancreatic cancer Acute pancreatitis Chronic pancreatitis ...

Insight Material

How does infective panniculitis present? Infective panniculitis, in general, has no specific features. The clinical presentation depends on: The type of organism Its virulence (how harmful it is) The route of inoculation The immune state of the individual. How is the diagnosis of infective panniculitis made? Whilst history is important, the diagnosis usually requires microbiological and ...

Final Conclusion

What is panniculitis? Panniculitis is a condition where the fat under the skin becomes inflamed. What is nodular panniculitis? Nodular panniculitis is characterised by one or multiple, recurrent, subcutaneous nodules. These commonly arise on the legs but can arise elsewhere on the body. Nodular panniculitis is associated with acute systemic symptoms such as fever, general malaise and abdominal ...

Males and females of any age are equally affected by the panniculitis associated with alpha-1-antitrypsin deficiency, and it can rarely arise in children. As alpha-1-antitrypsin deficiency is under-diagnosed, the true prevalence of panniculitis due to alpha-1-antitrypsin deficiency is difficult to ascertain. Introduction Panniculitis is a recognised, but rare complication of ฮฑ1-antitrypsin (A1AT) deficiency. It is mostly diagnosed in the homozygous PiZZ variant.