A 2014 paper in Pediatrics noted that a small number of children (six) exhibited an allergic reaction to methylisothiazolinone, and patients with that allergy should avoid products containing the ... Methylisothiazolinone will be banned in body lotions, deodorants, and other leave-on cosmetics sold in the European Union later this year. The European Commission’s Standing Committee on Cosmetic ...

Context Explanation

Methylisothiazolinone (MI) is a preservative. MI was initially used occupationally, in paints, adhesives/glues and cleaners etc, as a mixture with methylchloroisothiazolinone (MCI). Preservatives — particularly methylisothiazolinone, formaldehyde, and benzalkonium chloride — there has been a recent epidemic of airborne allergic contact dermatitis from methylisothiazolinone in water-based paints on freshly painted walls Paraphenylenediamine in hair dye and ammonium persulfate (hairdressing bleach) The most important classes of preservatives are parabens, formaldehyde -releasers, and isothiazolinones, including methylisothiazolinone. They all may cause dermatitis in some susceptible persons.

Insight Material

In many countries, regulations limit the concentration of preservatives and require preservatives to be listed on the package. Methylisothiazolinone (MI) is a related allergen which may show immunologic cross-reactions to octylisothiazolinone. MI has been found to cause high rates of contact allergic dermatitis and was declared the Contact Allergen of the year for 2013 by the American Contact Dermatitis Society. Who gets contact allergy to octylisothiazolinone?