Anticholinergic burden refers to the cumulative effect of taking one or more medications with anticholinergic properties, which inhibit the neurotransmitter acetylcholine. In older adults, an ... Medscape: Anticholinergic Medications Linked to Decline in Physical Performance in Older Adults Higher anticholinergic exposure was associated with accelerated decline in gait speed (-0.0132 m/s per year) and grip strength in older adults, with effects most pronounced within 4-6 years of ...

Context Explanation

The Anticholinergic Drug Scale (ADS), developed by Boustani et al., was created to address the issue of anticholinergic burden. This term refers to the cumulative effect of using multiple medications ... Monthly Prescribing Reference: Anticholinergics Tied to Physical Performance Decline in Older Adults Authors say findings support guidance to avoid these medications when possible. HealthDay News โ€” Anticholinergics are associated with physical performance decline in older adults, according to a study ...

Insight Material

News Medical: High use of anticholinergic drugs linked to increased cardiovascular disease risk People who use drugs with anticholinergic effects, including certain antidepressants, drugs for urinary incontinence and common antihistamines, are at higher risk of developing cardiovascular disease.