dermal melanocytosis - HEALTHY
Melanocytes arise from neural crest cells and populate the epidermis through migration. In all dermal melanocytosis subtypes, melanocyte migration is believed to be arrested in the dermis, leading to ... Nature: Prevalence of ocular and oculodermal melanocytosis in Spanish population with uveal melanoma The aim of this study was to determine the prevalence of ocular and oculodermal melanocytosis (ODM) among patients with uveal melanoma (UM) in a Spanish population.
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Ten (11 eyes) of 400 patients (2.7% ... Prevalence of ocular and oculodermal melanocytosis in Spanish population with uveal melanoma A-E: acral melanoma acral nevus atypical melanocytic nevi of the genital type atypical melanocytic proliferation atypical Spitz tumor (Spitz melanocytoma) BAP1 inactivated nevus / melanocytoma blue nevus / cellular blue nevus café-au-lait spot combined common acquired nevus congenital nevus cutaneous neurocristic hamartoma dermal melanocytosis ... Blue nevus / cellular blue nevus is characterized by a dermal proliferation of melanocytes, with typical clinical presentation of a blue to black macule, papule or nodule on the head, distal extremities or buttock These are lesions with a prominent dermal component whose biologic behavior is unclear and in which melanoma is the main diagnostic consideration. Answer A is incorrect because melanocytic hyperplasia is a general term for an increase in epidermal melanocytes, which may be benign, atypical or frankly malignant.
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Answer A is incorrect because adnexal spread and mature dermal component are also common features of atypical melanocytic nevus of genital type. Hence, the lack of maturation is the most concerning feature in this patient. Comment Here Reference: Pigmented lesions-vulva