atrophoderma - HEALTHY
Atrophoderma of Pasini and Pierini is a rare form of dermal atrophy characterised by asymptomatic slightly depressed areas with a well-defined ‘cliff-drop’ edge. Atrophoderma of Pasini and Pierini (APP) is a rare skin disorder affecting dermal collagen and presenting with dermal atrophy. The classic clinical manifestations of APP are hyperpigmented or hypopigmented, depressed areas of skin on the trunk or extremities (picture 1A-B).
Context Explanation
Atrophoderma is defined as a skin condition characterized by sharply demarcated gray-brown, atrophic lesions that are round to oval and depressed, typically without a violaceous border or induration. Idiopathic Atrophoderma of Pasini and Pierini is a rare skin disease which is thought to affect dermal collagen organization resulting in dermal atrophy. Considered to be a rare clinical variant of localized scleroderma or morphea, the characteristic lesions in atrophoderma of Pasini and Pierini (APP) consist of atrophic lesions or depressions rather than indurated plaques with lilac border. Atrophoderma of Pasini and Pierini is a rare skin condition that causes thinning of the skin, also known as dermal atrophy.
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Insight Material
It is characterized by one or more clearly defined dark patches on the skin, which are not hardened or inflamed. Atrophoderma of Pasini and Pierini (APP) is a rare, benign cutaneous condition characterized by the development of hyperpigmented depressions on the skin, primarily affecting the dermis. These lesions are typically oval or circular, with a distinct "cliff-drop" border and well-defined edges. Atrophoderma, also known as atrophoderma of Pasini and Pierini (APP) or idiopathic APP (IAPP), is a form of dermal atrophy characterized by oval, round, or irregularly shaped, brown to gray, smooth, atrophic, depressed plaques with well-demarcated, sharply sloping borders.